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ADSTILADRIN® (nadofaragene firadenovec

et al. Intravesical nadofaragene firadenovec gene therapy for BCG-unresponsive non-muscle-invasive bladder cancer: a single-arm,。

et al. From interferon to checkpoint inhibition therapy—a systematic review of new immune-modulating agents in Bacillus Calmette–Guérin (BCG) refractory non-muscle-invasive bladder cancer (NMIBC). Cancers. 2022;14(3):694. doi:10.3390/cancers14030694 10. Data on file. Ferring Pharmaceuticals, et al. Efficacy of intravesical nadofaragene firadenovec for patients with Bacillus Calmette-Guérin-unresponsive nonmuscle-invasive bladder cancer: 5-year follow-up from a phase 3 trial. J Urol. 2024;212(1):1-12. doi:10.1097/JU.0000000000004020 7. Moyer JA。

Inc; 2024. 4. Anktiva. Prescribing information. ImmunityBio, Nguyen M, Boorjian SA, Inc; 2024. 5. TICE BCG. Package insert. Merck Co, Durant A, Inc; 2022. 6. Narayan VM, CA. 8. Boorjian SA, et al. Real-world outcomes of nadofaragene firadenovec in BCG-unresponsive non-muscle invasive bladder cancer. Poster presented at: 2025 ASCO Genitourinary Cancers Symposium. February 13-15。

Wang CT, Dinney CPN. Intravesical gene therapy. Urol Clin North Am. 2020;47(1):93-101. doi:10.1016/j.ucl.2019.09.011 , Inc. July 2024. 11. Lu CS, Gabrielson A。

References: 1. ADSTILADRIN. Package insert. Ferring Pharmaceuticals, open-label, Shieh GS, repeat-dose clinical trial. Lancet Oncol. 2021;22(1):107-117. doi:10.1016/S1470-2045(20)30540-4 9. Deininger S, et al. Chemotherapeutics-induced Oct4 expression contributes to drug resistance and tumor recurrence in bladder cancer. Oncotarget. 2017;8(19):30844-30858. doi:10.18632/oncotarget.9602 12. Narayan VM, Konety BR。

2025; San Francisco。

et al. Intravesical gemcitabine and docetaxel in the treatment of BCG-naïve non–muscle invasive urothelial carcinoma of the bladder: updates from a phase 2 trial. J Clin Oncol. 2023;41(suppl 6):507. doi:10.1200/JCO.2023.41.6_suppl.507 3. Keytruda. Prescribing information. Merck Co。

Törzsök P, Mitterberger M, Inc; October 2025. 2. Patel SH, Collins C, Alemozaffar M, Alemozaffar M。

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